An Ayurvedic Product:
Ayurveda
is 5000 years old Indian Medical Science, which predominantly comprises herbal remedies.
HERBAVATE cream is a topical formulation containg the oil extract of various herbs.
It has been widely used in Indian system of traditional medicine for various skin
disorder and is found to be safe and effective. HERBAVATE could be an important
alternative to the long term management of various dermatological conditions like
eczema associated with itching, redness, scaling and thickening. Unlike steroids
which produce side effects on long term use it may be possible to use HERBAVATE
safely for long periods.
Herbavate Cream composition:
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Each 10 gm contains oil extract equivalent to:
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Calotropis
gigantea (Aak)
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:4gm,
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Curcuma
longa (Haldi)
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:0.5gm,
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Pongamia
glabra (Karanja)
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:0.1gm,
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Solanum
xanthocarpum (Kantakari)
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:0.2gm,
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Camphor
(Kapoor)
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:2% w/w,
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Apricot
oil
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:0.04ml,
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in a cream
base …….q.s.
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All ingredients have proven efficacy in Ayurveda.
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Herbavate - Healing
power of Herbs:
Beneficial
in eczema and a variety of Inflammatory and infectious skin conditions.
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A scientifically
formulated ideal combination developed in an attempt to balance the side effects
of the conventional therapy (e.g. Steroids) without compromising the therapeutic
efficacy
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Herbavate
comprises of biologically active medicinal principles extracted from 6 traditional
Indian Medicinal plants, which are documented in Ayurveda.
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5 way action due to six proven medicinal herbs
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Curcuma longa
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Calotropis gigantea
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Prunus armeniaca
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Solanum xanthocarpum
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Pongamia glabra
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Cinnamomum camphora
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Role of Turmeric in Herbavate:
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Curcuma longa (turmeric) has been used as a nontoxic
drug in Ayurveda for centuries to treat a wide variety of disorders including rheumatism
and skin diseases. Curcumin reportedly possesses several pharmacological properties
including antiinflammatory, antimicrobial, antiviral, antifungal, antioxidant, chemosensitizing,
radiosensitizing, and wound healing activities. Recently it also has been reported
to have potent immunomodulatory properties.
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It
modulates the activation of T cells, B cells, macrophages, neutrophils, natural
killer cells, and dendritic cells. Curcumin can also downregulate the expression
of various proinflammatory cytokines including TNF, IL-1, IL-2, IL-6, IL-8, IL-12,
and chemokines, most likely through inactivation of the transcription factor NF-?B.
Apparently curcumin is a pluripotent pharmacological agent that utilizes multiple
molecular pathways to leave its imprint on biological systems.
As Herabvate
works by modulating the immune response its long term use is not associated with
the side effects observed with Steroids which works by supressing the immune response.
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Calotropis gigantea:
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The roots
of Calotropis gigantea have been used in leprosy, eczema, syphilis, elephantiasis,
ulceration and cough in the Indian system of traditional medicine. It has been documented
to have anti-inflammatory, wound healing, immunomodulator, antimicrobial and antioxidant
properties.
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Pongamia glabra:
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Pongamia
glabra is one of the most commonly used medicinal plant reported to have antibacterial
properties agiainst gram negative and gram positive bacteria.
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Solanum xanthocarpum:
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The berries
of Solanum nigrum (Solanaceae) has been reported in the ancient Indian medicinal
literature with beneficial effects in inflammation and tuberculosis.
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Herbavate is manufactured
by modern techniques:
Medicinal
herbs in Herbavate Cream are purified, Standardised and analysed by modern analytical
method - Thin layer chromatography (TLC) for content & purity to ensure consistant
quality batch after batch.
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TLC (Thin Layer Chromotography)
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TLC identifies
therapeutically active marker compounds Viz. Alpha turmerone, beta-amyrin, glabrachromene
- 1 etc. present in Herbavate. Activity of all ingredients assured throughout the
shelf life by validating through stability studies, conducted as per WHO protocol.
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Therapeutic Rationale
of Herbavate:
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Mechanism of Action
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Antipruritic
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Antiinflammatory
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Antinociceptive
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Antimicrobial
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Immunomodulatory
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Calotropis
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<-------------------------------------------------------->
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Prunus
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<------------------>
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Pongamia
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<------------------>
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Cinnamomum
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<------------------>
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Curcumin
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<---------->
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<------------------>
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Solanum
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-
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<--------->
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-
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5 way mechanism of action:
To relieve
the symptoms of Eczema and a variety of inflammatory and infectious skin conditions,
without adverse effects of Steroids.
Herbavate
has shown remarkable results in acute Eczema. In chronic Eczema, the alleviation
is similar to the steroids without the accompanying side - effects.
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