An Ayurvedic Product:

Ayurveda is 5000 years old Indian Medical Science, which predominantly comprises herbal remedies. HERBAVATE cream is a topical formulation containg the oil extract of various herbs. It has been widely used in Indian system of traditional medicine for various skin disorder and is found to be safe and effective. HERBAVATE could be an important alternative to the long term management of various dermatological conditions like eczema associated with itching, redness, scaling and thickening. Unlike steroids which produce side effects on long term use it may be possible to use HERBAVATE safely for long periods.

Herbavate Cream composition:

Herbavate - Healing power of Herbs:
Beneficial in eczema and a variety of Inflammatory and infectious skin conditions.

• A scientifically formulated ideal combination developed in an attempt to balance the side effects of the conventional therapy (e.g. Steroids) without compromising the therapeutic efficacy
• Herbavate comprises of biologically active medicinal principles extracted from 6 traditional Indian Medicinal plants, which are documented in Ayurveda.

	5 way action due to six proven medicinal herbs       Curcuma longa Calotropis gigantea Prunus armeniaca         Solanum xanthocarpum Pongamia glabra Cinnamomum camphora
	Role of Turmeric in Herbavate:

Curcuma longa (turmeric) has been used as a nontoxic drug in Ayurveda for centuries to treat a wide variety of disorders including rheumatism and skin diseases. Curcumin reportedly possesses several pharmacological properties including antiinflammatory, antimicrobial, antiviral, antifungal, antioxidant, chemosensitizing, radiosensitizing, and wound healing activities. Recently it also has been reported to have potent immunomodulatory properties.     It modulates the activation of T cells, B cells, macrophages, neutrophils, natural killer cells, and dendritic cells. Curcumin can also downregulate the expression of various proinflammatory cytokines including TNF, IL-1, IL-2, IL-6, IL-8, IL-12, and chemokines, most likely through inactivation of the transcription factor NF-?B. Apparently curcumin is a pluripotent pharmacological agent that utilizes multiple molecular pathways to leave its imprint on biological systems. As Herabvate works by modulating the immune response its long term use is not associated with the side effects observed with Steroids which works by supressing the immune response.     Calotropis gigantea:   The roots of Calotropis gigantea have been used in leprosy, eczema, syphilis, elephantiasis, ulceration and cough in the Indian system of traditional medicine. It has been documented to have anti-inflammatory, wound healing, immunomodulator, antimicrobial and antioxidant properties.     Pongamia glabra:   Pongamia glabra is one of the most commonly used medicinal plant reported to have antibacterial properties agiainst gram negative and gram positive bacteria.     Solanum xanthocarpum:   The berries of Solanum nigrum (Solanaceae) has been reported in the ancient Indian medicinal literature with beneficial effects in inflammation and tuberculosis.

Herbavate is manufactured by modern techniques:

Medicinal herbs in Herbavate Cream are purified, Standardised and analysed by modern analytical method - Thin layer chromatography (TLC) for content & purity to ensure consistant quality batch after batch.

	TLC (Thin Layer Chromotography)
	TLC identifies therapeutically active marker compounds Viz. Alpha turmerone, beta-amyrin, glabrachromene - 1 etc. present in Herbavate. Activity of all ingredients assured throughout the shelf life by validating through stability studies, conducted as per WHO protocol.

Therapeutic Rationale of Herbavate: