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Clinical Studies

Three studies of varying duration have been carried out with Herbavate cream at various Medical Colleges in India. The first study was a non-comparative study of Herbavate of one month duration. In the second and third study Herbavate cream was compared with betamethasone a potent steroid.

Clinical Study 1:
Herbavate in Eczema

(Number of patients) = 32 out-patients with a clinical diagnosis of eczema

Duration: 4 weeks 

Treatment: Herbavate cream over the lesion twice daily

Conclusion: Due to the significant decline in the symptoms of skin conditions after using Herbavate for four weeks. Herbavate is able to manage and control the symptoms of Eczema.

Conclusion: Due to the significant decline in the symptoms of skin conditions after using Herbavate for four weeks. Herbavate is able to manage and control the symptoms of Eczema.

Clinical Study 2:
Herbavate cream vs. topical Betamethasone in Eczema

(Number of patients) = 119 out-patients with a clinical diagnosis of eczema

Duration: 4 weeks 

Treatment: Herbavate cream over the lesion twice daily

Conclusion:There is a significant Improvement in Mean Scores for Eczema Symptoms at 4th week of Herbavate Therapy Compared to Betamethasone. Hence Herbavate appears to be a safe alternate option to the long term management of eczema without side effects.

Table: Improvement in Mean Scores for Eczema Symptoms at Week 4 of Herbavate Therapy Compared to Baseline Scores
Symptom n Mean baseline score Mean score at week 4 Mean decrease in score Decrease in score (%)
Erythema 105 2.02±0.89 1.42±0.66 -0.60 -29.70*
Scaling 108 2.58±0.84 1.86±1.04 -0.72 -27.90*
Thickening 103 2.51±1.06 1.64±0.71 -0.87 -34.66*
Itching 103 2.71±1.08 1.85±0.75 -0.86 -31.73*
*p<0.001. Scores on a 4-point scale. Values are expressed as mean±standard deviation.

Conclusion: There is a significant Improvement in Mean Scores for Eczema Symptoms at 4th week of Herbavate Therapy Compared to Betamethasone. Hence Herbavate appears to be a safe alternate option to the long term management of eczema without side effects.

Clinical Study 3:
Herbavate cream vs. topical Betamethasone + Antibiotic in Eczema

(Number of patients) = 59 out-patients with a clinical diagnosis of eczema

Duration: 3 months 

Treatment: Herbavate cream or topical Betamethasone with Antibiotic over the lesion twice daily

Conclusion: The reduction appears in the mean score of the four symptoms with Herbavate for the period of 3 months is statistically almost equal to that of Bethametasone and antibiotics. Hence Herbavate appears to be a safe alternate option to the long term management of eczema.